Daflon (MPFF) is a proven venotonic that reduces haemorrhoidal bleeding and inflammation. Standard dose 500 mg twice daily for 3 months. Learn how it works and when to use it.
What Is Daflon and How Does It Help Piles?
Daflon is the brand name for micronised purified flavonoid fraction (MPFF) — a combination of diosmin (90%) and hesperidin (10%) derived from citrus fruits. It is classified as a venoactive drug — one that improves venous tone and reduces vascular permeability.
For piles patients, MPFF works through several mechanisms:
- **Reduces haemorrhoidal vein engorgement** by improving venous tone
- **Decreases vascular permeability** — reducing fluid leakage that causes swelling
- **Reduces the inflammatory cascade** in haemorrhoidal tissue
- **Shortens the duration and severity of acute bleeding episodes**
Clinical Evidence for Daflon in Piles
Multiple randomised controlled trials have confirmed MPFF's effectiveness for haemorrhoidal bleeding:
- Reduces bleeding episodes by approximately 70% compared to placebo
- Significantly reduces itching, mucus discharge and discomfort
- Most effective for Grade I–II internal piles
- Less effective for Grade III–IV as monotherapy (procedure needed)
Standard Dosage and Duration
- **Acute episodes:** 3000 mg/day (6 tablets of 500 mg) for 4 days, then 2000 mg/day (4 tablets) for 3 days = total 7-day acute protocol
- **Chronic/maintenance:** 500 mg twice daily (1000 mg/day) for 3 months — then review
MPFF is available in India under multiple brand names: Daflon, Venaflin, Flavokin, Hemolen. All contain the same active ingredient.
Who Benefits Most From Daflon
- Grade I–II piles with recurrent bleeding
- Patients not yet ready for or not requiring a procedure
- Adjunct to dietary correction during initial management
- Post-procedure to reduce recurrence risk
Side Effects
Generally very well tolerated. Mild effects include nausea, headache or mild gastrointestinal discomfort in a minority of patients.
Frequently Asked Questions
**Q: Can I take Daflon long-term for piles?** A: MPFF is safe for medium-term use (3–6 months). Long-term continuous use should be reviewed by a doctor — as Grade II–III piles that are not responding to 3 months of MPFF plus dietary correction typically need a procedure.
**Q: Is Daflon available over the counter in India?** A: Yes — MPFF preparations are available OTC in India. However, self-prescription without grading examination is not advisable.
Consult RectoRelief Hospital
For appropriate prescription and a complete treatment plan for your piles grade, book a consultation at RectoRelief Hospital.